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#aggregation
— Tuesday, January 06, 2026
(2 items)
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Polyserine domains are toxic and exacerbate tau pathology in mice.
(pnas.org)
Van Alstyne M
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Parker R
PNAS
2026-01-06
#aggregation
#neurodegeneration
#toxicity
#tauopathy
#transgenic
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Mass spectrometry footprinting reveals how kinetic stabilizers counteract transthyretin dynamics altered by pathogenic mutations.
(pnas.org)
Pinheiro F
…
Ventura S
PNAS
2026-01-06
#proteomics
#aggregation
#protein dynamics
#amyloid
#drug discovery