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Modular determinants of cleavage preference in GIY-YIG nucleases revealed by block-based DNA shuffling and directed evolution.
(academic.oup.com)
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Nucleic Acids Research 2026-01-05 | #mutagenesis #nuclease #protein design #directed evolution #dna recognition | |
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Argonaute-mediated RNA editing selectively repairs point mutations.
(academic.oup.com)
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Nucleic Acids Research 2026-01-05 | #gene therapy #rna editing #nuclease #argonaute |