#directed evolution — Monday, January 05, 2026 (2 items)
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Modular determinants of cleavage preference in GIY-YIG nucleases revealed by block-based DNA shuffling and directed evolution.
(academic.oup.com)
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Nucleic Acids Research 2026-01-05 | #mutagenesis #nuclease #protein design #directed evolution #dna recognition | |
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Directed evolution on compact landing pads yields highly efficient recombinases for large DNA integration.
(academic.oup.com)
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Nucleic Acids Research 2026-01-05 | #genome engineering #gene therapy #directed evolution #recombinase #base-editing |