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30
|
|
Eplontersen for Transthyretin Amyloid Cardiomyopathy.
(nejm.org)
|
Fontana M
…
Maurer MS
New England Journal of Medicine
2026-08-28
|
#amyloid
#cardiomyopathy
#clinical trial
#oligonucleotide
#therapeutics
|
|
22
|
|
Induced pluripotent stem cells from discovery to translation.
(nature.com)
|
Lee J
…
Wu JC
Nature Medicine
2026-08-27
|
#stem-cells
#regenerative medicine
#tissue engineering
#genome editing
#therapeutics
|
|
20
|
|
Safety and lipoprotein(a)-lowering effects of Kylo-11, a non-canonical, long-duration small interfering RNA targeting lipoprotein(a): a first-in-human, randomised, double-blind, placebo-controlled, phase 1 trial.
(linkinghub.elsevier.com)
|
Sarraju A
…
Nissen SE
The Lancet
2026-08-28
|
#clinical trial
#rnai
#therapeutics
#cardiovascular
#lipidomics
|
|
12
|
|
Structure-function analysis of the FCRL5-IgG1 Fc complex reveals an unappreciated pathway for B cell modulation by Fc-attenuated IgG.
(science.org)
|
Herpers BM
…
Georgiou G
Science Advances
2026-08-28
|
#antibody
#immunology
#crystallography
#b-cells
#therapeutics
|
|
11
|
|
Microbiome-based therapeutics for Clostridioides difficile infection: additive, subtractive, and modulatory strategies in modern clinical practice.
(tandfonline.com)
|
Cristian RE
…
Chifiriuc MC
Gut Microbes
2026-08-27
|
#microbiome
#cdi
#dysbiosis
#therapeutics
#fmt
|
|
9
|
|
Heritable transgenic schistosomes as a living platform for SARS-CoV-2 neutralizing antibody secretion.
(nature.com)
|
Ittiprasert W
…
Brindley PJ
Nature Communications
2026-08-26
|
#schistosomiasis
#transgenesis
#antibody
#crispr
#therapeutics
|
|
7
|
|
RIBOTAC-mediated degradation of hsa-microRNA-301a-3p suppresses TNBC bone metastasis.
(science.org)
|
Zhou W
…
Luan X
Science Advances
2026-08-26
|
#metastasis
#microrna
#breast cancer
#rna degradation
#therapeutics
|
|
5
|
|
Massively parallel characterization of RNA G-quadruplex stability and molecular recognition.
(academic.oup.com)
|
Martyr JG
…
Dominguez D
Nucleic Acids Research
2026-08-24
|
#rna
#g-quadruplex
#sequencing
#protein-binding
#therapeutics
|
|
4
|
|
Targeting CDKs in the RNAPII transcription cycle.
(nature.com)
|
Fisher RP
…
Geyer M
Nature Reviews Drug Discovery
2026-08-24
|
#transcription
#kinase
#cancer
#therapeutics
#dysregulation
|
|
3
|
|
Deciphering the comprehensive relationship between 5' UTR and 3' UTR sequences with deep learning.
(academic.oup.com)
|
Suga K
…
Hamada M
Bioinformatics
2026-08-26
|
#rna
#deep learning
#utr
#therapeutics
#translation
|
|
3
|
|
Ferroptosis: significance to zoonotic diseases and therapeutic prospects.
(tandfonline.com)
|
Tian L
…
Wang X
Emerging Microbes & Infections
2026-08-25
|
#ferroptosis
#zoonosis
#immunity
#infection
#therapeutics
|