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#selectivity  — top 20, last 14d

20 ℹ PI3Kdelta is selectively inhibited by roginolisib by stabilizing the C-terminal helix kalpha12. (nature.com) robot Vadas O … Hummer G Nature Communications 2026-10-09 #kinase #inhibitor #cancer #crystallography #selectivity
15 ℹ Insect-specific aldehyde synthase governs cuticle strength: a selective insecticide target. (science.org) robot Ding Y … Liu T Science Advances 2026-10-09 #insecticide #enzyme-inhibition #sclerotization #selectivity #cuticle
1 ℹ Development of A10P3C, an isoform-selective inhibitor of EGLN2, for targeting breast cancer. (pnas.org) robot Liang Q … Zhang Q PNAS 2026-10-01 #cancer #inhibitor #drug discovery #transcriptomics #selectivity