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#rna polymerase
— top 20, last 30d
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Hydrophobic unnatural base pair promotes trigger loop closure and catalysis in cellular RNA polymerase independent of hydrogen bonding.
(pnas.org)
Li Q
…
Wang D
PNAS
2026-08-12
#transcription
#cryo-em
#rna polymerase
#synthetic-nucleotides
#catalysis
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Structure of human cytoplasmic Pol II complex explains global transcription repression by GDOWN1.
(nature.com)
Schmitzova J
…
Cramer P
Nature Communications
2026-08-05
#transcription
#cryo-em
#rna polymerase
#assembly
#protein structure