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0
|
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Dysregulation of autophagosome-mitochondria contacts contributes to autophagy dysfunction and neurodegeneration in tauopathy.
(pnas.org)
|
Jia N
…
Cai Q
PNAS
2026-06-16
|
#autophagy
#neurodegeneration
#tauopathy
#mitochondria
#proteostasis
|
|
0
|
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Defective queuosine and i6A/ms2i6A modification of tRNATyr cause frameshifting and protein aggregation.
(academic.oup.com)
|
Sun Y
…
Ehrenhofer-Murray AE
Nucleic Acids Research
2026-06-22
|
#translation
#rna
#frameshifting
#proteostasis
#modification
|
|
0
|
|
IRE1 regulates the proteostasis of TDP-43/TARDBP in ALS/FTD through ribosome-associated quality control.
(pnas.org)
|
Liu D
…
Li S
PNAS
2026-06-24
|
#proteostasis
#neurodegeneration
#misfolding
#unfolded protein response
|
|
0
|
|
Reversible suppression of autophagy in a mouse model reveals neuronal resilience.
(science.org)
|
Eguchi T
…
Mizushima N
Science
2026-06-25
|
#autophagy
#neurodegeneration
#proteostasis
#neuropathology
|
|
0
|
|
Cellular assembly and functional resilience of the mammalian RNA exosome.
(link.springer.com)
|
Navalayeu T
…
Ameres SL
The EMBO Journal
2026-06-25
|
#proteostasis
#protein assembly
#ribonuclease
#crispr
#quality control
|
|
0
|
|
Proteostasis and unfolded protein response dynamics in human neuron/mouse glia co-cultures reveal a cell-specific maturation response.
(pnas.org)
|
Barny LA
…
Plate L
PNAS
2026-06-29
|
#proteostasis
#proteomics
#unfolded protein response
#neuronal-maturation
#co-culture
|
|
0
|
|
Tau protein as a regulator of mitochondrial function and dynamics.
(pnas.org)
|
Tsakiri E
…
Palikaras K
PNAS
2026-06-30
|
#neurodegeneration
#mitochondrial
#aging
#proteostasis
#stress response
|
|
0
|
|
PP2A phosphatase regulates Hippo signalling in dual manner.
(link.springer.com)
|
Sekar A
…
Ribeiro PS
The EMBO Journal
2026-07-07
|
#hippo
#phosphatase
#signaling
#proteostasis
|
|
0
|
|
Hypoxia rescues complex 1-associated disease caused by proteostatic defects.
(nature.com)
|
Garg A
…
Jain IH
Nature Metabolism
2026-07-08
|
#proteostasis
#mitochondrial
#neurodegeneration
#hypoxia
#proteolysis
|
|
0
|
|
Local autophagy impairment triggers brain-wide presynaptic remodeling and resilience.
(link.springer.com)
|
Toppe D
…
Sigrist SJ
The EMBO Journal
2026-07-08
|
#autophagy
#synaptic plasticity
#proteostasis
#neurodegeneration
#lifespan
|
|
0
|
|
The UFSP2-ODR4 complex spatially confines and dynamically controls UFM1 deconjugation to safeguard neuronal proteostasis.
(linkinghub.elsevier.com)
|
Mao G
…
Komatsu M
Molecular Cell
2026-07-09
|
#proteostasis
#ubiquitination
#neurodegeneration
#endoplasmic-reticulum
|