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23
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De novo design of cysteine proteases.
(nature.com)
|
Choi H
…
Baker D
Nature
2026-10-14
|
#proteolysis
#enzyme design
#catalysis
#protein design
#synthetic biology
|
|
15
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HURDLER: a cloning method to overcome length limits in designed repeat proteins.
(academic.oup.com)
|
Dai W
…
Zerbe O
Nucleic Acids Research
2026-10-13
|
#protein design
#cloning
#synthetic biology
#directed evolution
|
|
7
|
|
Structural basis and rational engineering of a thermophilic Cas13a for robust RNA detection.
(linkinghub.elsevier.com)
|
Oladeji SJ
…
Gao Y
Cell Chemical Biology
2026-10-13
|
#crispr
#rna
#diagnostics
#protein design
#structural biology
|
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4
|
|
Design of ancestral protein-glutaminase with improved thermal stability.
(journals.asm.org)
|
Ono T
…
Nakano S
Applied and Environmental Microbiology
2026-10-13
|
#protein design
#thermostability
#ancestral reconstruction
#enzyme
|
|
4
|
|
A bifunctional actuator to correct loss-of-function deficits in cardiac voltage-gated sodium channels.
(science.org)
|
Fossier L
…
Ben-Johny M
Science Advances
2026-10-09
|
#ion channel
#channelopathy
#arrhythmia
#cardiac
#protein design
|
|
2
|
|
Use of split intein and myotropic AAV vectors enables effective preclinical gene therapy for dysferlinopathy.
(science.org)
|
McCormack NM
…
Tasfaout H
Science Translational Medicine
2026-10-07
|
#gene therapy
#muscular dystrophy
#aav vectors
#protein design
#muscle-disease
|
|
2
|
|
Machine learning-assisted directed evolution of plant Rubisco.
(science.org)
|
McDonald JL
…
Wilson RH
Science Advances
2026-10-07
|
#protein design
#directed evolution
#machine learning
#enzyme kinetics
|
|
1
|
|
DeepSAP: An Integrated Generative and Predictive Deep-Learning Framework for Controllable Design of Self-Assembling Peptides.
(academic.oup.com)
|
Song Y
…
Deng X
Bioinformatics
2026-10-07
|
#deep learning
#peptide
#self-assembly
#protein design
#generative modeling
|
|
1
|
|
DyME: An MD-based engine exploiting HTP mutagenesis for protein engineering and recognition mimicry.
(journals.plos.org)
|
Guillem-Gloria PM
…
Pisabarro MT
PLOS Computational Biology
2026-10-07
|
#mutagenesis
#simulation
#protein design
#binding
#computational
|