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#obesity  — top 20, last 30d

20 ℹ UBT251, a novel triple GLP-1, GIP, and glucagon receptor agonist, in adults with overweight or obesity: A multicenter, randomized phase 2 trial. (linkinghub.elsevier.com) robot Zhou Z … Yan H Cell Metabolism 2026-10-07 #clinical trial #obesity #metabolic #pharmacology #cardiovascular
16 ℹ ALIX-dependent small extracellular vesicles from tissue-resident mesenchymal cells regulate pancreatic beta cell proliferation in obesity. (science.org) robot Uehara Y … Shimomura I Science Advances 2026-10-09 #obesity #exosome #metabolism #pancreatic #inflammation
15 ℹ Metabolic advantages of a high-protein, low-carbohydrate diet in in patients with metabolically unhealthy obesity. (linkinghub.elsevier.com) robot Guess N Cell Metabolism 2026-10-06 #metabolism #obesity #steatosis #nutrition #prediabetes
15 ℹ Diet-microbiome interactions enhance cancer immunotherapy in obesity. (linkinghub.elsevier.com) robot van Renterghem AWJ … Voest EE Cell Metabolism 2026-10-06 #microbiome #immunotherapy #immunity #cancer #obesity
11 ℹ Human genetic evidence challenges NCOA1 as a monogenic obesity gene. (linkinghub.elsevier.com) robot Delplanque J … Bonnefond A Cell Reports Medicine 2026-10-08 #obesity #genetics #pathogenic-variants #leptin-melanocortin #monogenic
7 ℹ Metabolic and neural responses to ultraprocessed foods: a randomized, controlled, crossover study. (nature.com) robot Hutelin Z … DiFeliceantonio AG Nature Metabolism 2026-10-05 #metabolism #nutrition #neuroimaging #insulin #obesity
4 ℹ Escherichia coli-derived enterobactin is associated with delayed gut microbiome maturation in infants born to mothers with obesity. (journals.asm.org) robot Kovenskiy A … Kozhakmetov S mSystems 2026-10-07 #microbiome #amr #metagenomics #virulence #obesity
4 ℹ Survodutide Once Weekly in Adults with Obesity and Type 2 Diabetes. (nejm.org) robot Wharton S … Kaplan LM New England Journal of Medicine 2026-10-01 #clinical trial #diabetes #obesity #pharmacotherapy #metabolism
3 ℹ Beyond BMI: The diet-microbiome context of the obesity paradox. (linkinghub.elsevier.com) robot Tao EW … Chen YX Cancer Cell 2026-09-30 #microbiome #metabolism #immunotherapy #obesity
3 ℹ Maternal obesity imprints methylation marks in oocytes to drive intergenerational metabolic dysfunction. (nature.com) robot Han L … Wang Q Nature Metabolism 2026-10-02 #methylation #epigenetics #obesity #metabolism #transgenerational
2 ℹ Retatrutide, a Triple Hormone Receptor Agonist, for Treatment of Obesity. (nejm.org) robot Jastreboff AM … Wang Y New England Journal of Medicine 2026-09-29 #obesity #pharmacotherapy #agonist #metabolism
1 ℹ Retatrutide in adults with obesity and type 2 diabetes (TRIUMPH-2): a double-blind, parallel-group, randomised, placebo-controlled, phase 3 trial. (linkinghub.elsevier.com) robot Bellido V … Taylor A The Lancet 2026-09-29 #clinical trial #diabetes #obesity #pharmacotherapy
1 ℹ Leptin-sensitive hypothalamic Lepr+/Glp1r+ neurons limit hyperphagia and weight gain in diet-induced obesity. (link.springer.com) robot Belmont-Rausch DM … Pers TH The EMBO Journal 2026-10-02 #obesity #leptin #transcriptomics #hypothalamus #feeding
0 ℹ Adipose ILC2s depend on acetyl-CoA carboxylase 1 to maintain metabolic health. (linkinghub.elsevier.com) robot Karagiannis F … Wilhelm C Cell Metabolism 2026-09-23 #metabolism #obesity #immunity #inflammation #adipose
0 ℹ An RNA thermogenic therapy to preserve lean mass and enhance metabolic health during GLP-1 weight loss. (pnas.org) robot Thorne AK … Bass J PNAS 2026-09-25 #obesity #thermogenesis #metabolism #rna therapeutics #adipose
0 ℹ A commensal-derived sugar protects against obesity by regulating immunometabolism. (linkinghub.elsevier.com) robot Tan CY … Surana NK Cell Host & Microbe 2026-09-23 #microbiome #obesity #immunometabolism #commensal #exopolysaccharide
0 ℹ Multivariate GWAS framework for family trios with parental phenotypes to control dynastic effects. (link.springer.com) robot Zhang S … Zhou JY BMC Bioinformatics 2026-09-28 #genome-wide association #mendelian randomization #family-studies #obesity #confounding
0 ℹ Combinatorial targeting of the miR-379/miR-410 cluster normalizes glucose and lipid homeostasis in male models of diabetes and obesity. (nature.com) robot Gil-Lozano M … Herzig S Nature Communications 2026-09-21 #metabolism #microrna #diabetes #obesity #hepatocyte
0 ℹ The Gibbs free energy landscape based on liver metabolome revealed thermodynamic robustness against fasting and obesity. (linkinghub.elsevier.com) robot Abekawa T … Kuroda S iScience 2026-09-24 #metabolomics #thermodynamics #metabolism #fasting #obesity
0 ℹ Cagrilintide and retatrutide combination therapy enhances weight loss and metabolic outcomes in obese male rats. (nature.com) robot Petersen J … Clemmensen C Nature Metabolism 2026-09-15 #obesity #metabolism #diabetes #peptide #proteomics