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20
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UBT251, a novel triple GLP-1, GIP, and glucagon receptor agonist, in adults with overweight or obesity: A multicenter, randomized phase 2 trial.
(linkinghub.elsevier.com)
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Zhou Z
…
Yan H
Cell Metabolism
2026-10-07
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#clinical trial
#obesity
#metabolic
#pharmacology
#cardiovascular
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16
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ALIX-dependent small extracellular vesicles from tissue-resident mesenchymal cells regulate pancreatic beta cell proliferation in obesity.
(science.org)
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Uehara Y
…
Shimomura I
Science Advances
2026-10-09
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#obesity
#exosome
#metabolism
#pancreatic
#inflammation
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15
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Metabolic advantages of a high-protein, low-carbohydrate diet in in patients with metabolically unhealthy obesity.
(linkinghub.elsevier.com)
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Guess N
Cell Metabolism
2026-10-06
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#metabolism
#obesity
#steatosis
#nutrition
#prediabetes
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15
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Diet-microbiome interactions enhance cancer immunotherapy in obesity.
(linkinghub.elsevier.com)
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van Renterghem AWJ
…
Voest EE
Cell Metabolism
2026-10-06
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#microbiome
#immunotherapy
#immunity
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#obesity
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11
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Human genetic evidence challenges NCOA1 as a monogenic obesity gene.
(linkinghub.elsevier.com)
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Delplanque J
…
Bonnefond A
Cell Reports Medicine
2026-10-08
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#obesity
#genetics
#pathogenic-variants
#leptin-melanocortin
#monogenic
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7
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Metabolic and neural responses to ultraprocessed foods: a randomized, controlled, crossover study.
(nature.com)
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Hutelin Z
…
DiFeliceantonio AG
Nature Metabolism
2026-10-05
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#metabolism
#nutrition
#neuroimaging
#insulin
#obesity
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4
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|
Escherichia coli-derived enterobactin is associated with delayed gut microbiome maturation in infants born to mothers with obesity.
(journals.asm.org)
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Kovenskiy A
…
Kozhakmetov S
mSystems
2026-10-07
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#microbiome
#amr
#metagenomics
#virulence
#obesity
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4
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Survodutide Once Weekly in Adults with Obesity and Type 2 Diabetes.
(nejm.org)
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Wharton S
…
Kaplan LM
New England Journal of Medicine
2026-10-01
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#clinical trial
#diabetes
#obesity
#pharmacotherapy
#metabolism
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3
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|
Beyond BMI: The diet-microbiome context of the obesity paradox.
(linkinghub.elsevier.com)
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Tao EW
…
Chen YX
Cancer Cell
2026-09-30
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#microbiome
#metabolism
#immunotherapy
#obesity
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3
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|
Maternal obesity imprints methylation marks in oocytes to drive intergenerational metabolic dysfunction.
(nature.com)
|
Han L
…
Wang Q
Nature Metabolism
2026-10-02
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#methylation
#epigenetics
#obesity
#metabolism
#transgenerational
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2
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|
Retatrutide, a Triple Hormone Receptor Agonist, for Treatment of Obesity.
(nejm.org)
|
Jastreboff AM
…
Wang Y
New England Journal of Medicine
2026-09-29
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#obesity
#pharmacotherapy
#agonist
#metabolism
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1
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|
Retatrutide in adults with obesity and type 2 diabetes (TRIUMPH-2): a double-blind, parallel-group, randomised, placebo-controlled, phase 3 trial.
(linkinghub.elsevier.com)
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Bellido V
…
Taylor A
The Lancet
2026-09-29
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#clinical trial
#diabetes
#obesity
#pharmacotherapy
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1
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|
Leptin-sensitive hypothalamic Lepr+/Glp1r+ neurons limit hyperphagia and weight gain in diet-induced obesity.
(link.springer.com)
|
Belmont-Rausch DM
…
Pers TH
The EMBO Journal
2026-10-02
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#obesity
#leptin
#transcriptomics
#hypothalamus
#feeding
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0
|
|
Multivariate GWAS framework for family trios with parental phenotypes to control dynastic effects.
(link.springer.com)
|
Zhang S
…
Zhou JY
BMC Bioinformatics
2026-09-28
|
#genome-wide association
#mendelian randomization
#family-studies
#obesity
#confounding
|