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#lysosomes
— top 20, last 30d
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2
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💬 0
Astrocytes mobilize a broader repertoire of lysosomal repair mechanisms than neurons.
(linkinghub.elsevier.com)
Smith EM
…
Maday S
iScience
2026-08-21
#autophagy
#lysosomes
#neurodegeneration
#proteostasis
#glia
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0
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💬 0
Allosteric switching of Ca(2+) permeability in the lysosomal ion channel TPC2 underpins biased agonist activation.
(link.springer.com)
Mu Q
…
Patel S
The EMBO Journal
2026-08-07
#calcium signaling
#ion channel
#biased agonism
#allosteric-regulation
#lysosomes
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0
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💬 0
Lysosomal dysfunction drives a transcriptional and epigenetic signature found in disease-associated microglia in neurodegenerative diseases.
(linkinghub.elsevier.com)
Balak CD
…
Glass CK
Immunity
2026-08-03
#transcriptomics
#neurodegeneration
#microglia
#epigenetics
#lysosomes
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0
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Atlas of lysosomal aging reveals a metabolite signature shared with lysosomal storage disorders.
(science.org)
Puszynska AM
…
Weissman JS
Science
2026-07-30
#aging
#lysosomes
#metabolomics
#lysosomal-storage-disorders
#neurodegeneration
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0
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💬 0
Unveiling the role of lysosomes in antigen processing and presentation.
(academic.oup.com)
Colangelo GS
…
Barbero LM
Journal of Immunology
2026-08-04
#immunity
#antigen-presentation
#autoimmunity
#lysosomes