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#leukemia
— top 20, last 14d
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10
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💬 0
Multidomain interaction governs the filamentous assembly of the dominant-negative DNMT3A R882H mutant.
(pnas.org)
Chen J
…
Song J
PNAS
2026-08-25
#cryo-em
#protein structure
#epigenetics
#methyltransferase
#leukemia
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8
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💬 0
Myeloproliferative Neoplasms.
(nejm.org)
Plo I
…
Vainchenker W
New England Journal of Medicine
2026-08-20
#myeloproliferative
#hematology
#jak2
#leukemia
#immunotherapy
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3
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💬 0
A phase 1 feasibility trial of BE-CAR33, an "off-the-shelf" base-edited CAR33 T cell therapy for acute myeloid leukemia.
(science.org)
Georgiadis C
…
Qasim W
Science Translational Medicine
2026-08-19
#immunotherapy
#car-t
#leukemia
#base-editing
#transplantation
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2
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💬 0
L-asparaginase reversibly suppresses CD40-mediated B cell activation and antigen-presenting function by metabolic restriction.
(linkinghub.elsevier.com)
Hadzic A
…
Theurich S
iScience
2026-08-21
#metabolism
#immunity
#immunosuppression
#lymphocyte
#leukemia
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2
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💬 0
Space radiation promotes clonal hematopoiesis and hematologic disease upon aging in a driver gene and sex-specific manner.
(linkinghub.elsevier.com)
Evans MA
…
Walsh K
iScience
2026-08-21
#hematopoiesis
#radiation
#clonal_expansion
#aging
#leukemia