#kras — top 20, last 30d
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Acquired resistance to the RAS(ON) multi-selective inhibitor daraxonrasib guides rational combination therapy strategies in pancreatic cancer.
(nature.com)
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Nature Medicine 2026-08-11 | #amr #pancreatic cancer #targeted therapy #kras #circulating tumor dna | |
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Bronsted-basic small molecules activate GTP hydrolysis in KRAS-Q61 mutants.
(nature.com)
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Nature Chemical Biology 2026-08-12 | #oncology #kras #inhibitor #gtpase #drug discovery | |
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Stress granules confer an early vulnerability in KRAS-driven pancreatic tumorigenesis.
(linkinghub.elsevier.com)
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Cell Reports 2026-08-10 | #pancreatic cancer #stress response #oncogenesis #tumorigenesis #kras |