#homologous recombination — top 20, last 14d
| 7 | ℹ |
A genome-scale adaptation map identifies the FANCM-RMI1/2 complex as an opposing modulator of cell fitness upon BRCA1 or BRCA2 loss.
(linkinghub.elsevier.com)
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Molecular Cell 2026-10-06 | #cancer #homologous recombination #genomic instability #synthetic lethality #parp-inhibitors | |
| 1 | ℹ |
Expanding the therapeutic scope of PARP inhibitors in breast cancer: current indications and future directions.
(jci.org)
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Journal of Clinical Investigation 2026-10-01 | #breast cancer #parp-inhibitors #homologous recombination #synthetic lethality #biomarker | |
| 1 | ℹ |
Germline homologous recombination deficiency influences TP53-mutant clonal hematopoiesis fitness during platinum and PARP inhibitor treatment.
(nature.com)
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Nature Genetics 2026-09-28 | #hematopoiesis #homologous recombination #clonal evolution #chemotherapy #neoplasms |