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4
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A biased allosteric modulator is a molecular glue for beta(2)AR dimerization.
(nature.com)
|
Shen J
…
Kobilka BK
Nature
2026-08-19
|
#gpcr
#allosteric
#dimerization
#cryo-em
#signaling
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1
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Microbial GAIN domains undergo autoproteolysis and enable release of diverse cell-surface-associated proteins.
(linkinghub.elsevier.com)
|
Brogan AP
…
Rudner DZ
Current Biology
2026-08-18
|
#gpcr
#autoproteolysis
#adhesion
#archaea
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1
|
|
Ligand-tuned extracellular domain dynamics are correlated with signaling states in an adhesion GPCR.
(science.org)
|
Cechova K
…
Vafabakhsh R
Science Advances
2026-08-14
|
#gpcr
#signaling
#conformational dynamics
#fret
#allostery
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0
|
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Cryo-EM structure of the bicarbonate receptor GPR30.
(elifesciences.org)
|
Kaneda S
…
Nureki O
eLife
2026-08-14
|
#cryo-em
#gpcr
#homeostasis
#pharmacology
|
|
0
|
|
Small molecule inhibitor of orphan GPCR dimerization improves host defense and blood pressure control in mice.
(jci.org)
|
Kwon J
…
Wettschureck N
Journal of Clinical Investigation
2026-08-03
|
#gpcr
#infection
#macrophage
#immunology
#hypertension
|
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0
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Factors modulating the assembly of human beta(2)-adrenergic receptor-beta-arrestin complexes.
(nature.com)
|
Wilhelm FM
…
Muller DJ
Nature Structural & Molecular Biology
2026-07-31
|
#gpcr
#signaling
#protein-protein interaction
#spectroscopy
#membrane
|