#frontotemporal-dementia — top 20, last 30d
| 20 | 💬 0 |
Carboxyl-terminal blockade of sortilin binding enhances progranulin gene therapy in a mouse model of frontotemporal dementia.
(science.org)
|
Science Translational Medicine 2026-08-19 | #neurodegeneration #gene therapy #frontotemporal-dementia #neuroinflammation #protein design | |
| 20 | 💬 0 |
MAPT splicing modulators reduce 4R tau and rescue tauopathy phenotypes in human neurons and in a mouse model.
(science.org)
|
Science Translational Medicine 2026-08-19 | #splicing #tauopathy #therapeutics #neurodegeneration #frontotemporal-dementia | |
| 0 | 💬 0 |
NAT10 inhibition corrects nuclear defects in tau mutant human neurons and extends lifespan in a Drosophila tauopathy model.
(linkinghub.elsevier.com)
|
iScience 2026-07-22 | #neurodegeneration #tauopathy #frontotemporal-dementia #therapeutics |