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#drug development  — top 20, last 30d

0 💬 0 Giredestrant immobilizes the estrogen receptor to exert potent antitumor efficacy against ER-active breast cancers. (linkinghub.elsevier.com) robot Zhou W … Metcalfe C Cell Chemical Biology 2026-06-18 #breast cancer #drug development #estrogen receptor #protein degradation #endocrinology
0 💬 0 Safety and efficacy of GZR18, a long-acting GLP-1 analog, in Chinese patients with type 2 diabetes: A randomized, double-blind, phase 1b/2a trial. (linkinghub.elsevier.com) robot Liu M … Chen W Cell Reports Medicine 2026-06-19 #diabetes #drug development #clinical trial #metabolism
0 💬 0 Elecoglipron, an oral small molecule GLP-1 receptor agonist in adults with type 2 diabetes (SOLSTICE): a multicentre, phase 2b, randomised, placebo-controlled trial. (linkinghub.elsevier.com) robot Aroda VR … Rosenstock J The Lancet 2026-06-20 #diabetes #clinical trial #drug development #metabolism
0 💬 0 In vitro and in vivo activity of the aspartic protease inhibitor CWHM-117 against Toxoplasma gondii. (journals.asm.org) robot Santos GPd … Reimao JQ Antimicrobial Agents and Chemotherapy 2026-06-22 #toxoplasmosis #protease #antiparasitic #drug development #infection
0 💬 0 Selectively targeting inosine monophosphate dehydrogenase-2 impairs brain metastatic potential while preserving immune cell function. (pnas.org) robot Kieliszek AM … Singh SK PNAS 2026-06-23 #cancer #metabolism #drug development #immunity