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#chromothripsis  — top 20, last 14d

5 💬 0 Hypertranscription caused by p53 deficiency triggers nucleotide insufficiency that induces replication stress and genomic instability. (linkinghub.elsevier.com) robot Zaatra W Ernst A Molecular Cell 2026-09-03 #genomic instability #replication stress #p53 #chromothripsis #tumorigenesis