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#cholesterol
— top 20, last 30d
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4
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Conformational switch of NPC1 epitomizes a lumen-to-membrane alternating access model for nonpolar substrates.
(pnas.org)
Wu X
…
Yan N
PNAS
2026-10-06
#cholesterol
#lysosomal
#transport
#structural
#niemann-pick
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0
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Dual functions of NPC1L1 for cholesterol transport: Cholesterol capture and regulation of inner-leaflet cholesterol accessibility.
(linkinghub.elsevier.com)
Yamanashi Y
…
Takada T
iScience
2026-09-24
#cholesterol
#transport
#membrane
#lipid
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0
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Cholesterol maintains the degradative capacity of lysosomes during clearance and recycling of dysfunctional mitochondria.
(nature.com)
Yang H
…
Saheki Y
Nature Communications
2026-09-16
#mitophagy
#lysosomes
#lipid metabolism
#cholesterol
#autophagy
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0
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Structure and function of TM6SF1 reveals role in mTORC1 signaling.
(pnas.org)
Hong S
…
Li X
PNAS
2026-09-14
#cryo-em
#signaling
#mtorc1
#cholesterol
#lysosome
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0
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The orientation of cholesterol's hydroxy group affects its membrane dynamics and intracellular transport.
(linkinghub.elsevier.com)
Lauritsen L
…
Wustner D
iScience
2026-09-15
#cholesterol
#membrane
#transport
#lipid
#biophysics