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A 5 + 1 polyene scaffold that selectively recognizes ergosterol's conjugated diene uncouples antifungal potency from host toxicity. (science.org)

Authors: Liu W … Wang Z Journal: Science Translational Medicine Published: 2026-10-21 DOI: https://doi.org/10.1126/scitranslmed.aei5968
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#antifungal #ergosterol #polyene #toxicity #selectivity

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