Heterozygous germline mutations in MSH3, and probably MLH3, act as classical tumour suppressors, leading to excess somatic deletion mutations, signature ID4 and increased colorectal cancer risk. (gut.bmj.com)

Authors: Soriano I … Tomlinson I Journal: Gut Published: 2026-09-11 DOI: https://doi.org/10.1136/gutjnl-2026-338390