September 30, 2026

#diabetes — Wednesday, September 30, 2026 (3 items)

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1	ℹ	Cardiovascular safety of orforglipron versus insulin glargine in adults with type 2 diabetes at increased cardiovascular risk (ACHIEVE-4): a phase 3, event-driven, randomised, open-label, non-inferiority, active comparator trial. (linkinghub.elsevier.com)	Klein KR … Meskimen ER The Lancet 2026-09-30	#diabetes #cardiovascular #safety #glp-1 #pharmacotherapy
0	ℹ	Decomposing population differences in type 2 diabetes through a high-resolution GWAS of ~600,000 individuals with East Asian ancestry. (nature.com)	Saito K … Terao C Communications Biology 2026-09-30	#diabetes #genome-wide association #ancestry #polygenic #metabolism
1	ℹ	Akkermansia muciniphila protects diabetes-associated cognitive decline by enhancing leucine catabolism and suppressing neuronal excessive mitophagy. (tandfonline.com)	Ye X … Zheng H Gut Microbes 2026-09-30	#microbiome #diabetes #cognition #mitophagy #metabolism