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#natural-killer-cells
— Wednesday, September 23, 2026
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RNF43 p.G659fs leads to natural killer cell dysfunction in MSI-high colorectal cancer through PI3K/AKT/mTOR signaling and HLA-E up-regulation.
(science.org)
De Silva P
…
Giannakis M
Science Advances
2026-09-23
#colorectal cancer
#natural-killer-cells
#immunosuppression
#immunotherapy
#microsatellite_instability