#immunometabolism — Tuesday, September 15, 2026 (3 items)
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Reverse genetics in humanized mice reveals CARD8-mediated pyroptosis causing pancytopenia in human DPP9 deficiency.
(jci.org)
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Journal of Clinical Investigation 2026-09-15 | #pyroptosis #inflammasome #hematopoiesis #humanized-mice #immunometabolism | |
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Acute activation of Gq-signaling in pancreatic islet macrophages inhibits insulin secretion through AMPK-sphingolipid axis.
(jci.org)
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Journal of Clinical Investigation 2026-09-15 | #macrophage #insulin #immunometabolism #signaling #obesity | |
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ENPP1 buffers extracellular cGAMP in brown adipose tissue to limit insulin resistance.
(linkinghub.elsevier.com)
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Cell Reports 2026-09-15 | #metabolism #insulin resistance #inflammation #immunometabolism #adipose tissue |