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#selectivity
— Tuesday, September 01, 2026
(2 items)
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Mechanism of gating and isoform-specific inhibition in renal CLC chloride channels.
(pnas.org)
Chien CT
…
Maduke M
PNAS
2026-09-01
#cryo-em
#channels
#inhibition
#selectivity
#pharmacology
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Design and structural basis of selective nonsteroidal inhibitors of aster cholesterol trafficking.
(pnas.org)
Kim H
…
Tontonoz P
PNAS
2026-09-01
#cholesterol
#inhibitor
#protein structure
#drug design
#selectivity