#pathogenicity — Monday, August 31, 2026 (2 items)
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Conserved water molecules shape the pathogenicity of missense variants in human proteins.
(academic.oup.com)
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Molecular Biology and Evolution 2026-08-31 | #variants #pathogenicity #missense #protein structure #simulation | |
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SARS-CoV-2 Delta variant-specific ORF3a mutations destabilize lysosomal homeostasis to trigger lysosomal damage-mediated cell death.
(nature.com)
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Communications Biology 2026-08-31 | #virulence #pathogenicity #coronavirus #apoptosis #inflammation |