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#rnai
— Friday, August 28, 2026
(2 items)
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Surface chemistry governs sex-dependent responses to PEG and zwitterionic siRNA nanocarriers in primary macrophages.
(science.org)
Lanier OL
…
Peppas NA
Science Advances
2026-08-28
#nanoparticles
#rnai
#immunogenicity
#sex-differences
#macrophage
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Safety and lipoprotein(a)-lowering effects of Kylo-11, a non-canonical, long-duration small interfering RNA targeting lipoprotein(a): a first-in-human, randomised, double-blind, placebo-controlled, phase 1 trial.
(linkinghub.elsevier.com)
Sarraju A
…
Nissen SE
The Lancet
2026-08-28
#clinical trial
#rnai
#therapeutics
#cardiovascular
#lipidomics