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#lung cancer
— Saturday, August 22, 2026
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XPO1-mediated TRIM21 nuclear export reprograms TREM2+ macrophage polarization by targeting IRF3 to augment anti-PD-1 efficacy in small cell lung cancer.
(nature.com)
Du Q
…
Huang D
Nature Communications
2026-08-22
#immunotherapy
#macrophage
#lung cancer
#immunosuppression
#checkpoint-inhibitors