#proteostasis — Friday, August 21, 2026 (3 items)
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YTHDC1 functions as a molecular chaperone to suppress ALS-linked hnRNPA1 mutants from aggregation.
(nature.com)
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Nature Communications 2026-08-21 | #aggregation #neurodegeneration #proteostasis #chaperone | |
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Astrocytes mobilize a broader repertoire of lysosomal repair mechanisms than neurons.
(linkinghub.elsevier.com)
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iScience 2026-08-21 | #autophagy #lysosomes #neurodegeneration #proteostasis #glia | |
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Stress-induced secretory pathway disruption causes atypical metalloproteinase transport in PMM2-CDG.
(linkinghub.elsevier.com)
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iScience 2026-08-21 | #glycosylation #metalloproteinase #trafficking #proteostasis #congenital |