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#protein design — Monday, August 17, 2026 (4 items)

0 💬 0 AI-designed prion-capping proteins provide evidence that prion fibril ends are replication-competent surfaces that contribute to prion seeding activity and infectivity. (journals.asm.org) robot Slota JA Bailey-Elkin BA mBio 2026-08-17 #prion #amyloid #replication #protein design #infectivity
0 💬 0 Bridging Linguistic Reasoning and Biophysical Reality Toward Peptide Engineering via Instruction-Tuned Language Modelling. (academic.oup.com) robot Yang K Li P Bioinformatics 2026-08-17 #peptide #language-models #protein design #sequence design #machine learning
1 💬 0 Redesign of energetically frustrated regions rescues function in defective T4 clamp loaders. (academic.oup.com) robot Nimkar S Kuriyan J Molecular Biology and Evolution 2026-08-17 #mutagenesis #protein design #phage #atpase #dna replication
3 💬 0 Fifteen challenges for generative AI applications to cell biology. (linkinghub.elsevier.com) robot Dupire L Califano A Cell 2026-08-17 #ai #machine learning #cell biology #protein design