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0
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A self-iterative orthogonal base-editing platform enables multiplex N-to-N diversification and genome-scale functional screening in Escherichia coli.
(academic.oup.com)
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Fan X
…
Liu R
Nucleic Acids Research
2026-08-10
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#mutagenesis
#base-editing
#screening
#genome editing
#metabolic-engineering
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0
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Specific cleavage of 5' overhangs of non-target strand by Cas9 activated by target DNA binding.
(academic.oup.com)
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Lv S
…
Zheng L
Nucleic Acids Research
2026-08-10
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#crispr
#genome editing
#off-target
#diagnostics
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0
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CRISPR RNA architecture steers Cas9 catalysis and fidelity via a guide repeat clasp motif.
(academic.oup.com)
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Chilamkurthy R
…
Gagnon KT
Nucleic Acids Research
2026-08-10
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#crispr
#genome editing
#specificity
#rna structure
#structural biology
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0
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ETfinder: harnessing conserved C-terminal tails of single-stranded DNA-binding proteins for mining and engineering RecET systems in non-model microbial chassis.
(academic.oup.com)
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Lv D
…
Tan GY
Nucleic Acids Research
2026-08-10
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#genome editing
#recombineering
#synthetic biology
#metagenomics
#protein design
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