#catalysis — Monday, August 10, 2026 (2 items)
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The ZN domain acts as a dynamic switch coordinating multiple-step aminoacylation in bacterial leucyl-tRNA synthetase.
(academic.oup.com)
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Nucleic Acids Research 2026-08-10 | #synthetase #translation #catalysis #crystallography #antimicrobial-therapy | |
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Central guide-target pairing activates human Argonaute2 by uncoupling the N-PAZ and MID-PIWI lobes.
(pnas.org)
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PNAS 2026-08-10 | #cryo-em #rnai #gene silencing #structural biology #catalysis |