#ion channel — Friday, August 07, 2026 (2 items)
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Non-canonical pore architecture underlies constitutive gating of human retinal TRPM1.
(nature.com)
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Nature Communications 2026-08-07 | #cryo-em #ion channel #gating #structural biology #vision | |
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Allosteric switching of Ca(2+) permeability in the lysosomal ion channel TPC2 underpins biased agonist activation.
(link.springer.com)
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The EMBO Journal 2026-08-07 | #calcium signaling #ion channel #biased agonism #allosteric-regulation #lysosomes |