#polyamines — Tuesday, August 04, 2026 (2 items)
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Proteasome mutations associated with CANDLE syndrome cause altered neuronal development by dysregulating polyamine synthesis.
(jci.org)
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Journal of Clinical Investigation 2026-08-04 | #proteasome #neurodegeneration #polyamines #organoid #inborn-errors-metabolism | |
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ATP13A4 gates extracellular polyamine levels to control excitatory synaptogenesis.
(nature.com)
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Nature Communications 2026-08-04 | #polyamines #synaptogenesis #neurodevelopment #astrocyte #transport |