#base-editing — Friday, July 17, 2026 (3 items)
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Structure-guided engineering of AI-derived adenine base editors for nuclear and mitochondrial DNA editing.
(academic.oup.com)
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Nucleic Acids Research 2026-07-17 | #genome editing #base-editing #protein design #mitochondrial dna #specificity | |
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BASELINE: a CRISPR base editing platform for mammalian-scale single-cell lineage tracing.
(academic.oup.com)
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Nucleic Acids Research 2026-07-17 | #crispr #lineage tracing #single-cell #base-editing | |
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Synonymous mutations in essential genes infrequently produce fitness effects in human cell lines.
(academic.oup.com)
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Nucleic Acids Research 2026-07-17 | #mutagenesis #fitness #synonymous-mutations #base-editing |