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0
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Cryo-EM structures of human FANCJ reveal the mechanism of G-quadruplex unwinding and disease-associated mutations.
(nature.com)
|
You Q
…
Li H
Nature Communications
2026-07-15
|
#cryo-em
#g-quadruplex
#helicase
#dna repair
#structural biology
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0
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Hydration and hydrolysis define antibiotic resistance conferred by macrolide esterases.
(pnas.org)
|
Kelly ETR
…
Berghuis AM
PNAS
2026-07-15
|
#amr
#macrolides
#enzymology
#structural biology
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0
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Structure and dynamics of a four-protofilament microtubule from Heimdallarchaeales alpha/beta-tubulin.
(science.org)
|
Tran LT
…
Robinson RC
Science Advances
2026-07-15
|
#microtubule
#cryo-em
#archaea
#polymerization
#structural biology
|
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0
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Structural basis of kinesin-1 autoinhibition and its control of microtubule-based motility.
(science.org)
|
Ashaduzzaman M
…
Al-Bassam J
Science Advances
2026-07-15
|
#cryo-em
#motor-proteins
#autoinhibition
#microtubule
#structural biology
|
|
0
|
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A unified catalytic mechanism in bifunctional DNA glycosylases with an evolutionarily conserved aspartate-lysine dyad.
(nature.com)
|
Syed A
…
Tainer JA
Nature Communications
2026-07-15
|
#dna repair
#glycosylases
#catalysis
#structural biology
#oxidative-damage
|
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0
|
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DDX3X syndrome mutations lock DDX3X-RNA conformational states to drive persistent pathological condensation and neuronal death.
(academic.oup.com)
|
Ghosh P
…
Kesavardhana S
Human Molecular Genetics
2026-07-15
|
#neurodegeneration
#stress-granules
#neurodevelopmental
#protein misfolding
#structural biology
|
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0
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Induced ubiquitination of the partially disordered estrogen receptor alpha via a 14-3-3 directed molecular glue-PROTAC.
(nature.com)
|
Verhoef CJA
…
Cossar PJ
Nature Communications
2026-07-15
|
#ubiquitination
#protac
#protein degradation
#drug design
#structural biology
|