| 0 | 💬 0 |
Rational design of G(i)-biased CB1 agonist with reduced side effects.
(linkinghub.elsevier.com)
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Cell 2026-05-28 | #cryo-em #analgesia #drug design #biased signaling #structure-activity relationship | |
| 0 | 💬 0 |
A novel RAB5 binding site in human VPS34-CII that is likely the primordial site in eukaryotic evolution.
(elifesciences.org)
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eLife 2026-05-28 | #endocytosis #evolution #cryo-em #autophagy #protein-protein interaction |