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PCMT1 generates the C-terminal cyclic imide degron on CRBN substrates.
(nature.com)
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Nature Chemical Biology 2026-05-01 | #metabolism #ubiquitination #protein degradation #ptm | |
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Allosteric activation of RNF20/RNF40-RAD6A-mediated H2BK120 monoubiquitylation by H2BS112 GlcNAcylation.
(nature.com)
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Nature Chemical Biology 2026-05-01 | #transcription #cryo-em #histone #ubiquitylation #ptm |