#therapeutics — Thursday, April 23, 2026 (3 items)
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Divalent siRNA for prion disease.
(academic.oup.com)
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Nucleic Acids Research 2026-04-23 | #therapeutics #neurodegeneration #rnai #prion | |
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Direct targeting of C9ORF72 repeat RNA with fluorinated antisense oligonucleotides.
(academic.oup.com)
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Nucleic Acids Research 2026-04-23 | #therapeutics #neurodegeneration #antisense #repeat expansion #rna structure | |
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DUSP11 is an RNA triphosphatase that limits PspCas13b activity by destabilizing gRNA abundance in mammalian cells.
(academic.oup.com)
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Nucleic Acids Research 2026-04-23 | #screening #therapeutics #rna #crispr #knockdown |