#rna structure — Thursday, April 23, 2026 (3 items)
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Zalpha and Zbeta domains of ADAR1 and ZBP1 bind G-quadruplexes with nanomolar affinities, establishing Zbeta as a G-quadruplex-specific domain.
(academic.oup.com)
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Nucleic Acids Research 2026-04-23 | #g-quadruplex #rna structure #protein-dna binding | |
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Direct targeting of C9ORF72 repeat RNA with fluorinated antisense oligonucleotides.
(academic.oup.com)
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Nucleic Acids Research 2026-04-23 | #therapeutics #neurodegeneration #antisense #repeat expansion #rna structure | |
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Structure and sequence characteristics of 5'-stem-loop 1 modulate the escape from nsp1-mediated repression in SARS-CoV-2 variants.
(academic.oup.com)
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Nucleic Acids Research 2026-04-23 | #covid-19 #translation #variants #rna structure #viral evolution |