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#checkpoint
— Tuesday, April 14, 2026
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A C-degron regulates Chk1 kinase by allowing stability of inactive Chk1 and by making it short- lived upon activation.
(pnas.org)
Oh JH
…
Varshavsky A
PNAS
2026-04-14
#proteolysis
#kinase
#checkpoint
#ubiquitylation