#checkpoint — Monday, April 13, 2026 (2 items)
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Slx4 and Fun30/SMARCAD1 coordinate S-phase checkpoint regulation and replication fork protection in response to Top1-DNA crosslinks.
(academic.oup.com)
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Nucleic Acids Research 2026-04-13 | #dna repair #replication #genomic instability #homologous recombination #checkpoint | |
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ATR and TopBP1 oppose to control dormant origin activity and global replication dynamics, providing a first defense against replication stress.
(academic.oup.com)
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Nucleic Acids Research 2026-04-13 | #stress #replication #genome instability #checkpoint #atr |