#proteostasis — Wednesday, April 01, 2026 (2 items)
| 0 | ℹ |
ALS mutations disrupt self-association between the ubiquilin STI1 hydrophobic groove and internal placeholder sequences.
(link.springer.com)
|
The EMBO Journal 2026-04-01 | #neurodegeneration #phase separation #proteostasis #chaperone | |
| 0 | ℹ |
ZAP targets aberrant mRNA transcripts encoding proteins with defective signal peptides for degradation.
(link.springer.com)
|
The EMBO Journal 2026-04-01 | #proteostasis #er stress #quality control #mrna degradation #signal peptide |