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Structure of an initiation complex of mycobacterial helicase-nuclease AdnAB at a blunt double-strand break reveals local melting that engages the 3' tracking strand at the ratchet pawl of the helicase motor.
(academic.oup.com)
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Nucleic Acids Research 2026-03-19 | #cryo-em #recombination #dna repair #nuclease #helicase | |
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Structure of human lymphoid-specific helicase HELLS in its autoinhibited state.
(academic.oup.com)
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Nucleic Acids Research 2026-03-19 | #methylation #chromatin #cryo-em #protein structure #helicase |