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#neurodegeneration
— Tuesday, March 10, 2026
(4 items)
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Cellular circadian period and its deviation associate with Alzheimer's pathology and brain aging in cognitively impaired older adults.
(pnas.org)
Roh HW
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Kim EY
PNAS
2026-03-10
#aging
#neurodegeneration
#biomarker
#circadian
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Huntington's disease LIG1 modifier variant increases ligase fidelity and suppresses somatic CAG repeat expansion.
(pnas.org)
Lee E
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Seong IS
PNAS
2026-03-10
#neurodegeneration
#dna repair
#somatic mutation
#cag repeat
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Head-to-head comparison of brain-derived pTau217 and total pTau217 for brain amyloid and tau pathology classification.
(pnas.org)
Jiang Y
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Ip NY
PNAS
2026-03-10
#neurodegeneration
#amyloid
#biomarker
#tau
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Phagocytes as plaque catalysts: Human macrophages generate seeding-competent Abeta42 fibrils with cross-seeding activity.
(pnas.org)
Konstantoulea K
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Schymkowitz J
PNAS
2026-03-10
#aggregation
#neurodegeneration
#amyloid
#neuroinflammation
#microglia