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crRNA scaffold remodeling controls CRISPR-Cas12a activity for enhanced performance.
(academic.oup.com)
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Nucleic Acids Research 2026-02-24 | #crispr #nuclease #diagnostics #amplification | |
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Cruciform-forming AT/TA repeats are acted upon by structure-selective endonucleases and Rad51 prior to repositioning to the nuclear periphery for repair.
(academic.oup.com)
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Nucleic Acids Research 2026-02-24 | #recombination #dna repair #nuclease #replication #fragile sites |