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#proteolysis
— Tuesday, January 27, 2026
(3 items)
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Caspase-3 cleaves and activates the NADase SARM1 to promote apoptosis, linking two cell death mechanisms.
(pnas.org)
Shi J
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Tessier-Lavigne M
PNAS
2026-01-27
#metabolism
#neurodegeneration
#apoptosis
#proteolysis
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alpha2-macroglobulin function of thioester-containing proteins guards Drosophila from a bacterial protease via two immune-induced peptides.
(pnas.org)
Cai C
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Ferrandon D
PNAS
2026-01-27
#infection
#virulence
#immunity
#proteolysis
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A cytokine receptor-targeting chimera toolbox for expanding extracellular targeted protein degradation.
(pnas.org)
Kumru K
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Wells JA
PNAS
2026-01-27
#immunotherapy
#cytokine
#protein degradation
#proteolysis
#bispecific