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0
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Conformational dynamics of CRISPR-Cas type I-F-HNH inform nickase engineering in a cascade scaffold.
(academic.oup.com)
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Fuglsang A
…
Montoya G
Nucleic Acids Research
2026-01-22
|
#cryo-em
#crispr
#genome editing
#protein design
#nickase
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0
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Structures of naked mole-rat, tuco-tuco, and guinea pig ribosomes-is rRNA fragmentation linked to translational fidelity?
(academic.oup.com)
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Gutierrez-Vargas C
…
Frank J
Nucleic Acids Research
2026-01-22
|
#translation
#cryo-em
#rna
#ribosome
#fidelity
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0
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A comprehensive view on r-protein binding and rRNA domain structuring during early eukaryotic ribosome formation.
(academic.oup.com)
|
Gerhalter M
…
Bergler H
Nucleic Acids Research
2026-01-22
|
#assembly
#cryo-em
#rna
#protein-rna
#ribosome
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0
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Elucidating pathway-selective biased CCKBR agonism for Alzheimer's disease treatment.
(linkinghub.elsevier.com)
|
Wang JL
…
Sun JP
Cell
2026-01-22
|
#cryo-em
#neurodegeneration
#drug design
#biased agonism
#g protein signaling
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0
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Mechanisms of HSV-1 helicase-primase inhibition and replication fork complex assembly.
(linkinghub.elsevier.com)
|
Yu Z
…
Abraham J
Cell
2026-01-22
|
#cryo-em
#antiviral
#replication
#helicase
#herpesvirus
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0
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Butyrolactol A enhances caspofungin efficacy via flippase inhibition in drug-resistant fungi.
(linkinghub.elsevier.com)
|
Chen X
…
Wright GD
Cell
2026-01-22
|
#amr
#virulence
#cryo-em
#antifungal
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