#crispr — Thursday, January 22, 2026 (2 items)
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Conformational dynamics of CRISPR-Cas type I-F-HNH inform nickase engineering in a cascade scaffold.
(academic.oup.com)
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Nucleic Acids Research 2026-01-22 | #cryo-em #crispr #genome editing #protein design #nickase | |
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Structural plasticity enables broad cAn binding and dual activation of CRISPR-associated ribonuclease Cdn1.
(academic.oup.com)
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Nucleic Acids Research 2026-01-22 | #immunity #crispr #protein structure #nuclease |