| 0 | ℹ |
Transient acute neuronal activation response caused by high concentrations of oligonucleotides in the cerebral spinal fluid.
(academic.oup.com)
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Nucleic Acids Research 2026-01-22 | #neurotoxicity #cns #drug delivery #oligonucleotides #intrathecal | |
| 0 | ℹ |
Acute neuronal inhibition response caused by phosphorothioate antisense oligonucleotides following local delivery to the central nervous system.
(academic.oup.com)
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Nucleic Acids Research 2026-01-22 | #neurodegeneration #antisense #neurotoxicity #cns #neurotransmission |